XT-MULIN
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Tiamulin Hydrogen Fumarate
Chemical name:
(3aS,4R,5S,6S,8R,9R,9aR,10R)-6-Ethenyl-5-hydroxy-4,6,9,10-tetramethyl-1-oxodecahydro-3a,9-propano-3aH-cyclopentacycloocten-8-yl[[2-(diethylamino)ethyl]su lphanyl]acetate hydrogen (E)-butenedioate
Chemical abstract service (CAS) registry number: 55297-96-6
Structure formula:
Molecular formula: C28H47NO4S·C4H4O4
elative molecular mass: 609.82
Appearance: White or almost white crystal powder
Solubility: Soluble in water, freely soluble in anhydrous ethanol and soluble in methanol.
Melting temperature: Between 143℃ and 152℃.
pH: A 1% solution (g/ml) in water has a pH of 3.1 to 4.1.
Packaging and storage
Preserve in tight, light-resistant containers, and store at room temperature.

XT-MULIN
Pharmacological properties
Preserve in tight, light-resistant containers, and store at room temperature.
Tiamulin fumarate is a semi-synthetic diterpene antibiotic. The mode of action is by inhibition of ribosomal protein synthesis in sensitive bacteria. It is a bacteriostatic antibiotic and the following organisms show sensitivity in vitro:
Brachyspira: Brachyspira hyodysenteriae, Brachyspira pilosicoli
Mycoplasmas: Mycoplasma hyopneumoniae, M.hyorhinis, M. hyosynoviae, Ureaplasma spp.
Gram-positive: Staphylococcus spp., Streptococcus spp., Corynebacterium pyogenes.
Gram-negative: Pasteurella spp., Klebsiella pneumoniae, Actinobacillus (Haemophilus) spp., Fusobacterium necrophorum, Bacteroides spp., Campylobacter coli, Lawsonia intracellularis.
Following oral administration, tiamulin fumarate is rapidly absorbed and peak serum concentrations are achieved 2~4 hours after administration and concentrates in some tissues e.g. lung. Following absorption, it is rapidly metabolized and excreted.
Indications
For the treatment of chronic respiratory disease in chicken, the treatment, prevention and control of swine dysentery caused by Brachyspira hyodysenteriae and complicated by Fusobacterium and Bacteroides spp. As an aid in the control of the enzootic pneumonia complex in pigs.
Usage and dosage
Mix with feed or water:
For pig: Every 1000kgs feed, 40~100g Tiamulin fumarate, for 5~10 days consecutively.
For Chicken: Every 1L water, 125~250mg Tiamulin fumarate, for 5 days consecutively.
Withdrawal period: 7 days for pig; 5 days for chicken.
Delivery form
Tiamulin API 98% in 20kg/drum with 5 years of shelf life;
Tiamulin 80% granule in 20kg/drum with 2 years of shelf life;
Tiamulin 10% powder and granule in 25kg/bag with 2 years of shelf life;

20kg drum packing of Tiamulin 98% and 80%

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Products on pallets